The park maintains ecosystem functions that are essential for the lives of communities and local people in northern La Paz: climate regulation, watershed protection, water provision for the entire Iturralde Province, mitigation of carbon dioxide emissions and thus climate change.

Through safeguarding wild plants that were the origin of vital agricultural products for human consumption, Madidi also strengthens mitigation and adaptation possibilities in the face of climate change. The high Andes and its valleys are the center of origin for Andean grains and tubers, like the potato, oca, papalisa, quinua and masua, whereas the Amazon forests are the source for cacao, custard Apple, manioc, peanut and pineapple.